During a visit to Lichfield Cathedral on the start of the week, King Charles was confronted by a individual who questioned him about Prince Andrew's connections with disgraced financier Epstein.
The man inquired how long the King had been aware about his sibling's relationship with Jeffrey Epstein, and also raised doubts about whether he had asked the authorities to "cover up" for Prince Andrew.
Amid the protest, there were crowds of fans and applause for the monarch, who was visiting the region for an engagement.
The Duke of York's connections with Epstein have been under close examination in recent weeks. The prince, who relinquished his titles earlier this month, has strongly denied any wrongdoing.
"How long have you known about Prince Andrew and Epstein? Have you asked the authorities to cover up for him?"
The monarch ignored the questions but continued greeting fans, some of whom shouted "Long live the King". One fan can be overheard asking him for a hug.
A female bystander outside the venue was also heard telling the heckler to "leave" and to "shut up".
The controversy over Prince Andrew's links to Jeffrey Epstein has been brought back into focus by misconduct claims detailed in Ms. Giuffre's recently released memoir.
In the publication, the accuser claims she had sex with the royal on three separate occasions, including once with Jeffrey Epstein and "eight other young girls"
Andrew, who reached a financial settlement with Ms Giuffre in 2022, has repeatedly denied any wrongdoing. In a previous interview, he told BBC Newsnight he did not remember meeting her "at all", and that they "did not have any sort of sexual contact."
But in recent times, new inquiries have been asked about how he is able to finance his way of life despite not being a active member of the royal family.
The revelation that he has only ever paid a nominal fee on his Windsor mansion has heightened the scrutiny over his housing situation - even though he made large payments up front, including for renovations.
The Liberal Democrats said he should be called in front of members of parliament to give testimony about his rental agreement of his lodge.
But last week, the authorities refused to give parliamentarians time to debate the prince's status or his home, despite growing pressure for scrutiny.
Buckingham Palace has not issued a statement on whether Prince Andrew might move out of his current residence - or where he might go.
Escritora apasionada y viajera incansable, Elena comparte sus experiencias para inspirar a otros en su camino de autodescubrimiento.